Congratulations to Dr. Amol Patwardhan MD, PhD for being selected for the College of Medicine's Cliical Excellence Award. These awards are awareded to faculty members who exceed all standards of clinical excellence and inspire us regarding how we should serve and care for patients. Dr. Patwardhan is the Co-Director of our Chronic Pain Management Clinic, he has been with our department since 2014,
New location for Department of Anesthesiology
The Department of Anesthesiology moved into its new operating rooms on Monday April 9th that are located on the 3rd floor of the recently dedicated Tower 1, a 9 story, 670,000 square foot hospital, part of the Banner University Medical Center Tucson expansion project. The new peri-operative space includes 22 state of the art operating rooms, including 2 hybrid ORs, dedicated regional block and procedure rooms, office space for the Board Runner, Peri-Operative Medical Director and Director for Clinical Operations. A new Anesthesiology Library contains computers for charting as well as space for breaks between cases. New on-call rooms are located in separate Resident and Attending call suites that are in close proximity to operating rooms and will be a comfortable place to rest between clinical duties. Tower 1 has a beautiful sunny cafeteria (Level 1) with indoor and outdoor seating options, a coffee bar (Level 2) with mountain views and an outdoor roof-top patio (Level 4), all within a minute’s walk from the operating rooms. Also located in Tower 1 are procedural areas including Cardiology laboratories (Cath and EP), Interventional Radiology, MRI and CT scanner (Level 2). Level 5 houses the new OB center with OB Triage, Labor and Delivery rooms, OB operating rooms and pre- and post-partum rooms. All Adult ICUs will eventually relocate to Tower 1, with MICU (Level 7) and Surgical ICU (Level 8) being the first to relocate. The Cardio-vascular ICU will move in early May (Level 6). Faculty and staff will have convenient parking in Parking Garage C located just to the west of Tower 1 main entrance.
Stuart Hameroff MD and the Center for Consciousness Studies (‘CCS’) have received $153,000 from the Penrose Institute for clinical studies of transcranial ultrasound (‘TUS’) for treatment of dementia, brain trauma, addiction and mood disorders. He will be collaborating with Drs John JB Allen and Jay Sanguinetti in Psychology, Bellal Joseph in Surgery, Rich Amini in Emergency Medicine, and Todd Vanderah and Tally Largent-Milnes in Pharmacology. TUS has been shown to improve mood and cognitive function in humans, reverse effects of Alzheimer’s and brain trauma in animals, and could prove useful in treatment and/or prevention of post-operative cognitive dysfunction (POCD). The first clinical study showing TUS effects on mental states in humans was done by Hameroff and departmental colleagues (including Drs Boyle and Lucas) and published in the journal Brain Stimulationin in 2013.
The CCS-sponsored conference ‘The Science of Consciousness 2019’ will be held June 25-28 in Interlaken, Switzerland, in the Alps, near famous mountain peaks Eiger, Monk and Jungfrau. The program is excellent, including a workshop on how anesthetics act to specifically erase consciousness. Dr Hameroff is conference co-organizer, and will give several talks during the 4 day event. Click Here to read more.
University of Arizona Anesthesiology faculty Amol Patwardhan, MD, PhD and Mohab Ibrahim, MD, PhD both received notice of awards from NIH this month. Dr. Patwardhan, MD, PhD received an NIH-K08 Mentored Clinician-Scientist Award while Dr. Ibrahim, MD PhD was awarded an RO1. This marks the first time in many years that the Department of Anesthesiology has NIH funding.
Amol and Mohab represent the kind of success that can be achieved at the UA when clinician-scientists team up with outstanding basic scientists to tackle patient-related issues. Both investigators work closely with members of the Department of Pharmacology including Chairman Todd Vanderah, PhD; Frank Porreca, PhD, and Rajesh Khanna, PhD and Philip Malan, MD, PhD. (see https://pharmacology.arizona.edu/faculty). “This mentoring team has been a tremendous help for both Amol and Mohab and I am grateful for their dedication towards the development of these outstanding faculty members” said Dr. Dull. In fact, the depth of expertise on this mentoring team could not be found in most major research universities and is testament to the strength of our basic science department. The Departments of Anesthesiology and Pharmacology have enjoyed close ties for many years and we look forward to developing this collaboration into other clinically-relevant areas and leveraging this success in the recruitment of NIH-funded faculty into both departments.
Amol Patwardhan, MD, PhD
Dr. Patwardhan is an interventional pain physician, anesthesiologist and pharmacologist who studies novel mechanisms for inhibiting spinal pain transmission. His grant will assess the molecular mechanism by which contulakin-G (CGX), a peptide derived from snail venom, produces analgesia but without adversely affecting motor neuron function. Developing novel therapeutic compounds that are not related to opioids represent a huge opportunity in anesthesiology and neuro-pharmacology. Dr. Patwardhan and his team have proposed several hypotheses regarding the sites of action for CGX and plan to characterize the receptors and channels that are inhibited by CGX. A second major aspect of these studies is the observation that CGX does not result in tolerance, a common and rate limiting aspect of many pain medications. Characterizing how to avoid the development of tolerance for analgesics opens the possibility of improving the efficacy of existing analgesic drugs. We look forward to following the success of this very talented team of scientists.
Dr. Amol Patwardhan receives NIH Mentored Clinician-Scientist Award.
Mohab Ibrahim, MD PhD
Dr. Ibrahim is also an interventional pain physician, anesthesiologist and pharmacologist. His research focuses on the treatment of chronic pain in patients with HIV. Antiretroviral therapy, the mainstay of HIV treatment, is associated with an increased incidence of chronic pain. Dr. Ibrahim and his research team completed a pilot study to determine if different wavelengths of light have specific analgesic effect. They found that rats with chronic, HIV-related neuropathic pain experienced analgesia when exposed to green light in the range of 525 nm for 8 hours per day. In this 5-year NIH funded study, Dr. Ibrahim will study the mechanisms by which green light induces analgesia. Specifically, they will characterize neuroinflammatory pathways in the brain and spinal cord to understand how green light reduces neuropathic pain. Non-pharmacological therapies hold great promise for the treatment of chronic pain as they are cost-effective, devoid of most drug-related side effects and economically scalable for use in medically challenged areas, cultures and countries.