Clinical Trials

The Department of Anesthesiology faculty are involved in clinical research that covers a broad base of anesthesia subspecialties, including ambulatory, cardiovascular, neurosurgical, obstetric, pediatric, transplantation, and chronic pain anesthesia management. Patient and volunteer human studies are reviewed and monitored by the University of Arizona Human Subjects Protection Program.

Ongoing Clinical Trials

• A Phase 4 Randomized, Active-Comparator Controlled Clinical Trial to Study the Safety of Sugammadex (MK-8616) for the Reversal of Neuromuscular Blockade Induced by Either Rocuronium Bromide or Vecuronium Bromide in American Society of Anesthesiologists (ASA) Class 3 or 4 Subjects​ ​

Principal Investigator: Peter R Lichtenthal, MD

• Double Blind Prospective Study of IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery 

​Principal Investigator: Peter R Lichtenthal, MD

• RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain 

​Principal Investigators: Mohab Ibrahim, PhD., MD and Amol Patwardhan, PhD., MD

• A Study to Characterize the Relationship Between Select Objective Metrics and Clinical Outcomes in Chronic Pain Patients Treated With Boston Scientific Neurostimulation Systems 

​Principal Investigators: Mohab Ibrahim, PhD., MD and Amol Patwardhan, PhD., MD

• The Effect of Light Therapy on Post-Surgical Pain 

Principal Investigators: Mohab Ibrahim, PhD., MD

• The Effect of Light Therapy on Chronic Pain  

Principal Investigators: Mohab Ibrahim, PhD., MD

• Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients 

Principal Investigators: Mohab Ibrahim, PhD., MD

 

Current Studies

• Cell Saver use in Pediatric Hip Surgery

​Principal Investigator: Peter R Lichtenthal, MD

• Does Planned Intervention Improve the Experience for Children Undergoing Orthopedic Surgery,

​Principal Investigator: Peter R Lichtenthal, MD

• Types of Corticosteroids used in Epidural Injections that Improved Pain and Function for Non-malignant Chronic Pain Patients

​Principal Investigator: Amol Patwardhan, PhD., MD

• Determining the Relationship between Duration of Pain and Response to Treatment : A Retrospective Study

​Principal Investigator: Amol Patwardhan, PhD., MD

• Development and Calibration of Non-Invasive Regional Oximeter System

​Principal Investigator: Daniel Redford, MD

 

Completed Studies

• A Randomized, Assessor-Blind, Dose-Ranging Phase IIIB, Multicenter Trial Comparing The Intubating Conditions And Time Course Of Block Of Three Different Intubating Doses (0.45 Mg/Kg, 0.6 Mg/Kg, And 1.0 Mg/Kg) Of Zemuron® In Pediatric And Adolescent Subjects Under General Anesthesia

• A Randomized, Double-blind, Double-dummy, Dose-ranging, Active and Placebo-Controlled study of Single-dose Oral Rolapitant Monotherapy for the Prevention of Postoperative Nausea and Vomiting

• An Open-Label, Non-randomized, Multicenter, Ascending Dose by Age, Single- and Multiple-Dose Evaluation of the Effectiveness, Safety, and Tolerability of Oxymorphone HCl Immediate-Release Oral Liquid for Acute Postoperative Pain in Pediatric Subjects

• Performance Evaluation of the cobas b 123 POC system Bilirubin parameter using Neonatal blood

• Evaluation of ACCU-CHEK® Inform II System for Testing Arterial, Venous and Neonatal Heel Stick Samples in Critically Ill Patients

• Obesity-Mediated Hypercoagulability: Role of Hemeoxygenase-1

• Hemolysis-Mediated Hypercoagulability in Hemodialysis Patients: Role of Hemeoxygenase-1

• Migraine Headache Modulation of Coagulation

• Effects of Tobacco Smoking on Carbon Monoxide-Mediated Enhancement of Coagulation and Fibrinolysis

• Carbon Monoxide-Mediated Hypercoagulability in Patients with Cancer

• Survey on Anesthesiology Residency Applicants Use of Media in Selection of Residency

 

 

For additional information:

Vangie Steinbrenner

Research Specialist, Sr., (520) 626-3099